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Cardiomyocyte injury: mechanism of doxorubicin toxicity effects
doi: 10.18081/pcij/2378-5225/014-12/73-82 Pathophysiology of Cell Injury Journal Volume 3, Issue 2, pages 73-82 December 2014 Monica Vlaia; Mariela Hoang; Veronica Urzúa; Hugo Scammells; Sevgi González-Hernández Abstract Doxorubicin is part of a group of anthracycline antibiotics used in many treatment of solid and hematological malignancy. Doxorubicin use is limited by cumulative, dose-related, progressive myocardial cell injury that may […]
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Nur77 has a critical role in ovarian cancer progression through the regulation of the TGF-β signaling pathway
doi: 10.18081/pcij/2378-5225/014-12/60-72 Pathophysiology of Cell Injury Journal Volume 3, Issue 2, pages 60-72 December 2014 Alex J Danielson; Neil K Barnes; Stephen T Gurantz; Borg A Dunne; Leo Chung; Jan H Turner; Van G Porter Abstract Ovarian cancer is characterized by malignant transformation of ovarian epithelial, stromal, or germ line cells, the TGF-β pathway […]
Protects against cell injury and infection: activation of immune system/AhR
doi: 10.18081/pcij/2378-5225/014-12/46-59 Pathophysiology of Cell Injury Journal Volume 3, Issue 2, pages 46-59 December 2014 Ashley H. Schrenk; Rimpei Abe; Malcolm Scammells; Philip Frugier Abstract Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor is a ligand-activated transcription factor that serves as a receptor for various environmental toxins. The study used male mice […]
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Critical role of E6 oncoprotein in cervical cancer: involved in cell proliferation, angiogenesis and apoptosis
Pathophsiology of Cell Injury Journal Volume 1, Issue 1, pages June 2013 Brian S.Singer; Jone A. Fishbein; Stefan K Blino Abstract Cervical cancer represents one of the most common malignancies in women worldwide and predominantly affects women of poor socioeconomic status. Persistent infection with high-risk human papilloma virus (HPV) is an essential factor for development […]
Critical role of E6 oncoprotein in cervical cancer: involved in cell proliferation, angiogenesis and apoptosis Pathophsiology of Cell Injury Journal Volume 1, Issue 1, pages 9-19 June 2013 Brian S.Singer; Jone A. Fishbein; Stefan K Blino Abstract References Clifford GM, Smith JS, Plummer M, Muñoz N, Franceschi S. Human papillomavirus types […]
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Critical role of E6 oncoprotein in cervical cancer: involved in cell proliferation, angiogenesis and apoptosis
doi: 10.18081/pcij/2378-5225/014-12/35-45 Pathophysiology of Cell Injury Journal Volume 3, Issue 2, pages 35-45 December 2014 Brian S. Singer; Jone A. Fishbein; Stefan K. Blino Abstract Cervical cancer represents one of the most common malignancies in women worldwide and predominantly affects women of poor socioeconomic status. Persistent infection with high-risk human papilloma virus (HPV) […]